SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.7
USERS' SCORE
Good
Based on 10 Reviews
8.6
Supplement Facts
Serving Size:  1 Softgel
Amount Per Serving
%DV
Calories
15
 
Total Fat
1.5 g
2%‡
Evening Primrose Seed Oil (Oenothera biennis)
1,300 mg
GLA (Gamma-Linolenic Acid)
130 mg

Top Medical Research Studies

9
Evening primrose oil improves vascular health
Effect of dietary supplementation with evening primrose oil on vascular thrombogenesis in hyperlipemic rabbits.
Enhances cardiovascular disease understanding
We investigated how evening primrose oil affects cardiovascular health in rabbits fed a high-fat diet. Over six weeks, we found that it contributed to lower cholesterol levels and improved beneficial HDL-cholesterol. Additionally, the oil boosted prostacyclin synthesis, which plays a key role in keeping blood vessels healthy.

Our analysis showed that evening primrose oil reduced platelet adhesion and the size of arterial wall lesions. This suggests it may support better vascular health by enhancing the endothelium's ability to prevent blood clots.
Read More
9
Evening primrose oil shows promise
Dietary gamma-linolenic acid suppresses aortic smooth muscle cell proliferation and modifies atherosclerotic lesions in apolipoprotein E knockout mice.
Study relevant for heart disease
We explored the effects of dietary gamma-linolenic acid, found in evening primrose oil, on heart health in genetically modified mice prone to cardiovascular issues.

Over a period of 15 weeks, these mice were fed various diets, including those rich in gamma-linolenic acid.

Our observations showed that diets containing this oil slowed the growth of aortic smooth muscle cells and reduced the size of atherosclerotic lesions. However, overall cholesterol levels did not show significant changes.

Thus, while evening primrose oil benefits certain aspects of cardiovascular health, its impacts on overall lipid profiles remain limited.
Read More
9
Evening primrose oil lowers blood pressure
Dietary N-6 and N-3 fatty acids and salt-induced hypertension in the borderline hypertensive rat.
Study shows dietary impacts
We explored how dietary n-3 and n-6 fatty acids influence blood pressure, particularly under salt-loading conditions, using borderline hypertensive rats. In this study, we observed that evening primrose oil significantly lowered blood pressure, even below normal levels, while other oils like fish and sunflower also helped in reducing the pressor response. However, the beneficial effects did not depend on food or electrolyte intake. These findings indicate that dietary fats like evening primrose oil may help manage salt-induced blood pressure increases.
Read More

Most Useful Reviews

8.8
Health improvement
A quality supplement with excellent ingredients. I purchased it for my lovely mother. The doctor recommended the drug alongside others for overall support of the cardiovascular system and to alleviate inflammation in the joints. Additionally, it helps maintain heart health. Since starting, my mother’s health has improved, her joints are no longer aching, and her sleep has enhanced. We are very pleased with the results; I view this supplement as high quality and reliable.
Read More
8.8
Improves heart health
Evening primrose offers multiple benefits, particularly for cardiovascular health, as it helps lower cholesterol and sugar levels. It also effectively mitigates PMS and menopause symptoms. I take one capsule daily with dinner, and I feel it enhances my overall wellbeing remarkably.
Read More
8.8
Better health
A quality supplement with good ingredients. I bought it for my mother. The doctor recommended it alongside other drugs for general support of the cardiovascular system and to reduce inflammation in the joints, as well as to maintain heart health. My mother’s health has improved, her joints no longer ache, and her sleep quality has increased. We are very pleased with the results; I consider the supplement to be high quality and reliable.
Read More

Medical Researches

SCIENTIFIC SCORE
Possibly Effective
Based on 16 Researches
7.7
  • All Researches
9
Evening primrose oil shows promise
Dietary gamma-linolenic acid suppresses aortic smooth muscle cell proliferation and modifies atherosclerotic lesions in apolipoprotein E knockout mice.
Study relevant for heart disease
We explored the effects of dietary gamma-linolenic acid, found in evening primrose oil, on heart health in genetically modified mice prone to cardiovascular issues.

Over a period of 15 weeks, these mice were fed various diets, including those rich in gamma-linolenic acid.

Our observations showed that diets containing this oil slowed the growth of aortic smooth muscle cells and reduced the size of atherosclerotic lesions. However, overall cholesterol levels did not show significant changes.

Thus, while evening primrose oil benefits certain aspects of cardiovascular health, its impacts on overall lipid profiles remain limited.
Read More
9
Evening primrose oil improves vascular health
Effect of dietary supplementation with evening primrose oil on vascular thrombogenesis in hyperlipemic rabbits.
Enhances cardiovascular disease understanding
We investigated how evening primrose oil affects cardiovascular health in rabbits fed a high-fat diet. Over six weeks, we found that it contributed to lower cholesterol levels and improved beneficial HDL-cholesterol. Additionally, the oil boosted prostacyclin synthesis, which plays a key role in keeping blood vessels healthy.

Our analysis showed that evening primrose oil reduced platelet adhesion and the size of arterial wall lesions. This suggests it may support better vascular health by enhancing the endothelium's ability to prevent blood clots.
Read More
9
Evening primrose oil lowers blood pressure
Dietary N-6 and N-3 fatty acids and salt-induced hypertension in the borderline hypertensive rat.
Study shows dietary impacts
We explored how dietary n-3 and n-6 fatty acids influence blood pressure, particularly under salt-loading conditions, using borderline hypertensive rats. In this study, we observed that evening primrose oil significantly lowered blood pressure, even below normal levels, while other oils like fish and sunflower also helped in reducing the pressor response. However, the beneficial effects did not depend on food or electrolyte intake. These findings indicate that dietary fats like evening primrose oil may help manage salt-induced blood pressure increases.
Read More
8
Evening primrose oil mitigates thrombotic risk
Evening primrose oil or forskolin ameliorates celecoxib-enhanced upregulation of tissue factor expression in mice subjected to lipopolysaccharide-induced endotoxemia.
Relevant study on cardiovascular safety
We explored the impact of evening primrose oil (EPO) on the cardiovascular risks associated with celecoxib, a pain reliever linked to increased clotting factors. Using a mouse model of endotoxemia, we tested EPO alongside celecoxib for a month and found that it effectively reduced elevated tissue factor activity and overall clotting risks induced by celecoxib.

Our results suggested that combining EPO with celecoxib could provide a preventative strategy against potential thrombotic events in patients taking the medication. Overall, EPO showed promise in mitigating celecoxib's adverse cardiovascular effects.
Read More
8
Evening primrose oil reduces platelet aggregation
Effect of evening primrose oil on platelet aggregation in rabbits fed an atherogenic diet.
Findings indicate limited clinical relevance
We evaluated the effects of evening primrose oil supplementation on platelet aggregation in rabbits fed an atherogenic diet. Over six weeks, we divided 40 male rabbits into four groups to measure platelet behavior and related factors.

Our findings revealed that the atherogenic diet significantly increased platelet aggregation. However, the addition of evening primrose oil decreased this hyperaggregation back to levels seen in rabbits with normal diets. While EPO showed promising effects on platelet function, we observed no significant long-term benefits on cardiovascular health.
Read More

User Reviews

USERS' SCORE
Good
Based on 10 Reviews
8.6
  • All Reviews
  • Positive Reviews
  • Negative Reviews
8.8
Health improvement
A quality supplement with excellent ingredients. I purchased it for my lovely mother. The doctor recommended the drug alongside others for overall support of the cardiovascular system and to alleviate inflammation in the joints. Additionally, it helps maintain heart health. Since starting, my mother’s health has improved, her joints are no longer aching, and her sleep has enhanced. We are very pleased with the results; I view this supplement as high quality and reliable.
Read More
8.8
Improves heart health
Evening primrose offers multiple benefits, particularly for cardiovascular health, as it helps lower cholesterol and sugar levels. It also effectively mitigates PMS and menopause symptoms. I take one capsule daily with dinner, and I feel it enhances my overall wellbeing remarkably.
8.8
Better health
A quality supplement with good ingredients. I bought it for my mother. The doctor recommended it alongside other drugs for general support of the cardiovascular system and to reduce inflammation in the joints, as well as to maintain heart health. My mother’s health has improved, her joints no longer ache, and her sleep quality has increased. We are very pleased with the results; I consider the supplement to be high quality and reliable.
Read More
8.8
Relieves cardiovascular symptoms
The effects of evening primrose oil are undeniable, especially for me in alleviating PMS and other women's health concerns. I initially bought it for my mother, but upon using it myself, I noticed a notable improvement in skin texture and a significant reduction in discomfort during critical days. My mother benefited from fewer menopause symptoms as well. With consistent use, I found not only relief from PMS but also a heightened interest in libido. It’s remarkable how primrose has enhanced both our lives.
Read More
8
Cholesterol reduction
The quality is superb, with good ingredients that positively affect health. There is no age restriction and no fish in the composition. The packaging is tidy, and benefits include reduced cholesterol, and thicker hair. Inflammation subsides, and heart health is supported. It also aids skin and immune system health and alleviates PMS discomfort.
Read More

Frequently Asked Questions

No FAQs are available for this product and symptom.
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